Does Induction Agent Choice Affect post intubation hypotension?

Rapid sequence intubation can be associated with peri or post intubation hypotension and in a small group of patients, cardiac arrest. In the lecture on Resuscitative sequence intubation (July 2024 Podcast), we looked at some of the risk factors associated with this complication and how reduce the chances of this occurring.

Although there is little evidence that the induction agent makes a difference, the results of smaller studies has seen a move towards Ketamine as a preferred induction agent.

This study compared the incidence and severity of post intubation hypotension, with different induction agents, in one regional emergency department.

The Study

Tamest Z et al. Does the choice of induction agent in rapid sequence intubation in the emergency department influence the incidence of post-induction hypotension? EMA 2024 36, 340-347
PMID: 3801839

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