PARAMEDIC-3 Trial: Drug Route in OHCA
Nov 07, 2024
In response to the uncertainty of which route is better for drug administration in Out-of-Hospital Cardiac Arrest (OHCA) ie., intraosseous (I/O) or intravenous (IV), "we conducted the PARAMEDIC-3 trial to determine the clinical effectiveness of an intraosseous-first strategy, as compared with an intravenous-first strategy, in adults with out-of- hospital cardiac arrest."
This study showed that the use of an I/O-first strategy did not result in higher 30-day survival than an IV-first strategy.
The Study
Couper K et al. A Randomised Trial of Drug Route in Out-of-Hospital Cardiac Arrest. NEJM October 31st 2024(1)
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